Associate Professor of Department of Chemical Pathology
Office: (852) 3763 6034
Address: Room 306D, CUHK Li Ka Shing Medical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong
- Immune cell mediated tissue regeneration
- Cardiovascular regeneration in diabetes
- Development of checkpoint blocking antibodies for stem cell transplantation
- Li J, Yang KY, Tam RCY, Chan VW, Lan HY, Hori S, Zhou B, Lui KO*. “Regulatory T-cells regulate neonatal heart regeneration by potentiating cardiomyocyte proliferation in a paracrine manner.” Theranostics (accepted), 2019. *Correspondence
- Leung CS, Yang KY, Li X, Chan VW, Ku M, Waldmann H, Hori S, Tsang JCH, Lo YMD, Lui KO*. “Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T-cells.” Genome Medicine, 2018; 10:71. *Correspondence
- Leung OM, Li J, Li X, Chan VW, Yang KY, Ku M, Ji L, Sun H, Waldmann H, Tian XY, Huang Y, Lau J, Zhou B, Lui KO*. “Regulatory T cells promote apelin mediated sprouting angiogenesis in type 2 diabetes.” Cell Reports, 2018; 24:1610-1626. *Correspondence
- Tang J, Li Y, Huang X, He L, Zhang L, Wang H, Yu W, Pu W, Tian X, Nie Y, Hu S, Wang QD, Lui KO, Zhou B. (2018) Fate Mapping of Sca1+ Cardiac Progenitor Cells in the Adult Mouse Heart. Circulation. 138:2967-2969.
- Li Y, Lui KO*, Zhou B*. “Reassessing endothelial-to-mesenchymal transition in cardiovascular diseases.” Nature Review Cardiology, 2018; 15:445-456. *Correspondence
- Li Y, He L, Huang X, Issa Bhaloo S, Zhao H, Zhang S, Pu W, Tian X, Li Y, Liu Q, Yu W, Zhang L, Liu X, Liu K, Tang J, Zhang H, Cai D, Adams RH, Xu Q, Lui KO, Zhou B. “Genetic Lineage Tracing of Non-Myocyte Population by Dual Recombinases.” Circulation, 2018; 138:793-805.
- Lui KO*, Howie D, Ng SW, Liu SB, Chien KR, Waldmann H*. “Tolerance induction to human stem cell transplants with extension to their differentiated progeny.” Nature Communications, 2014; 5:5629. *Correspondence
- Zangi L#, Lui KO#, von Gise A, Ma Q, Ebina W, Ptaszek LM, Spater D, Xu HS, Tabebordbar M, Gorbatov R, Sena B, Nahrendorf M, Briscoe DM, Li RA, Wagers AJ, Rossi DJ, Pu WT, Chien KR. “Modified mrna directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.” Nature Biotechnology, 2013; 31:898-907. #Equal contribution
- Lui KO*, Zangi L, Silva EA, Bu L, Sahara M, Li RA, Mooney DJ, Chien KR*. “Driving vascular endothelial cell fate of human multipotent isl1(+) heart progenitors with VEGF modified mRNA.” Cell Research, 2013; 23:1172-1186. *Correspondence
- Lui KO, Boyd AS, Cobbold SP, Waldmann H, Fairchild PJ. “A role for regulatory t cells in acceptance of esc-derived tissues transplanted across an major histocompatibility complex barrier.” Stem Cells, 2010; 28:1905-1914.