Prof. LI, Gang

 Professor

Personal Information

Professor of Orthopaedics and Traumatology  

Office: (852) 3505 2731
Email: gangli@cuhk.edu.hk
Address: Room 74038, 5/F, Lui Che Woo Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T., Hong Kong

Expertise

  1. Stem Cell Therapy Clinical Applications
  2. Limb Deformity Correction and Reconstruction

Specialized Research Areas

  1. Distraction Osteogenesis Mechanisms and Novel Clinical Applications
  2. Stem Cell Biology and Cellular Therapies
  3. Musculoskeletal Tissue Engineering

Selected Publications

  1. Xu J, Feng Q, Lin S, Yuan W, Li R, Li J, Wei K, Chen X, Zhang K, Yang Y, Wu T, Wang B, Zhu M, Guo R, Li G*, Bian L. “Injectable stem cell-laden supramolecular hydrogels enhance in situ osteochondral regeneration via the sustained co-delivery of hydrophilic and hydrophobic chondrogenic molecules.” Biomaterials, 2019; 210:51-61.
  2. Kang H, Yang BG, Zhang KY, Pan Q, Yuan WH, Li G*, Bian LM. “Immunoregulation of macrophages by dynamic ligand presentation via ligand–cation coordination.” Nature Communication, 2019 April; 10(1):1696.
  3. Kang H, Wong SHD, Pan Q, Li G*, Bian L. “Anisotropic ligand nanogeometry modulates the adhesion and polarization state of macrophages.” Nano Lett, 2019; 19(3):1963-1975.
  4. Lin WP, Xu LL, Pa Q, Lin SE, Feng L, Wang B, Chen SX, Li Y, Wang HX, Li YC, Wang Y, Lee WYW, Sun D, Li G*. “Lgr5-overexpressing mesenchymal stem cells augment fracture healing through regulation of Wnt/ERK signaling pathways and mitochondrial dynamics.” The FASEB Journal, 2019.
  5. Lin SE, Cui L, Chen GH, Huang JP, Yang YH, Zou KJ, Lai YX, Wang XL, Zuo LY, Wu T, Cheng JCY, Li G*, Wei B, Lee WYW. “PLGA/β-TCP composite scaffold incorporating salvianolicacid B promotes bone fusion by angiogenesis and osteogenesis in a rat spinal fusion model.” Biomaterials, 2019, 196: 109-121.
  6. Xu J, Sun YX, Wu TY, Liu Y, Shi L, Zhang JF, Kang QL, Chai YM, Li G*. “Enhancement of bone regeneration with the accordion technique via HIF-1α/VEGF activation in a rat distraction osteogenesis model.”  Journal of Tissue Engineering and Regenerative Medicine, 2018; 12(2):e1268-e1276.
  7. Xu LL, Liu YM, Sun YX, Wang B, Xiong YP, Lin WP, Wei QS, Wang HB, He W, Wang B, Li G*. “Tissue source determines the differentiation potentials of mesenchymal stem cells- a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue.” Stem Cell Research & Therapy, 2017; 8(1):275.
  8. Lin SE, Lee WYW, Feng Q, Xu LL, Wang B, Man GCW, Chen YF, Jiang XH, Bian LM, Cui L, Wei B, Li G*. “Synergistic effects on mesenchymal stem cell-based cartilage regeneration by chondrogenic preconditioning and mechanical stimulation.” Stem Cell Research & Therapy, 2017; 8(1):221.
  9. Wang B, Lee WYW, Huang B, Zhang JF, Wu TY, Jiang XH, Wang CC, Li G*. “Secretome of human fetal mesenchymal stem cells ameliorates replicative senescence of human adult mesenchymal stem cells.” Stem Cells and Development, 2016; 347(2):360-6.
  10. Yin Zi, Guo J, Wu TY, Chen X, Xu LL, Lin SE, Sun YX, Chan KM, Ouyang HW, Li G*. “Stepwise differentiation of mesenchymal stem cells augments tendon-like tissue formation and defect repair in vivo.” Stem Cells Translational Medicine, 2016; 5(8):1106-16.