Clinical Trials and Precision Medicine

application of systems biology approaches and patient-derived induced pluripotent stem cells to address disease pathogenic mechanisms and drug targeting

Clinical Application of MSCs

April 12th, 2019|

An endeavor to investigate the role of hMSCs in regulating hematopoietic stem cell fate and their therapeutic potential to treat lupus nephritis, spinocerebellar ataxia and diabetes in different animal models, and has established clinical trials [...]

TGFβ1-Dnmts axis control the hepatic plasticity of MSCs

September 12th, 2018|

Transl Res. 2017 Apr;182:61-74.e8. Stem Cell Reports. 2017 Jul 11;9(1):247-263 The irreversibility of developmental processes in mammalian cells has been challenged by rising evidence that de-differentiation of hepatocytes occurs in adult liver. However, the underlying [...]

MSCs Isolation and Hepatic Tissue Engineering

January 12th, 2018|

Prof. Oscar Lee's first important research achievement was the discovery of differentiation potential of stem cells from mesodermal origin into hepatocytes of endodermal origin, and being the first to design a novel 2-step protocol to [...]

  • Clinical Trials and Precision Medicine

Clinical Trials and Precision Medicine

December 12th, 2017|

Cell-based therapy – Autologous chondrocyte implantation, a patch of cartilage defect made by the patient’s own chondrocytes. Technically, doctors will take a tiny piece of healthy articular cartilage, around 200mg, size like a couple [...]