Tissue Engineering for Regenerative Medicine

functional, biomimetic biomaterials with tissue and disease modification activities

Label-free Cell Analysis

May 31st, 2022|

Label-free cell analysis is a promising technology that is broadly applicable to the biomedical sciences but cannot be easily accomplished without artificial intelligence. Simply put, it is very tedious and time consuming for research [...]

Musculoskeletal Tissue Engineering and Regeneration

October 12th, 2018|

The musculoskeletal system is an intricate network comprised of hard and soft tissues including bone, tendon, and muscle and functions to facilitate body movement. Injuries and diseases affecting the musculoskeletal system dramatically impacts our quality [...]

Engineering of Bio-instructive Matrices in Vitro

July 12th, 2018|

The ECM is a biomaterial designed by nature, which has undergone more than 500 million years of material optimization. It signals cells using a combination of three major communication planes (biochemical composition, biomechanical properties and [...]

Extracellular Matrix Biology and Regenerative Medicine

April 12th, 2018|

Urea-extracted tissue ECM exhibits tissue-specific bioactivity. (A) Effect of soluble urea extracted ECMs on human mesenchymal stem cells (hMSCs) pellet culture. Gene expression analysis on D21 showed tenogenesis of tendon ECM (tECM) and chondrogenesis of [...]

Biomaterial Fabrication and Development

February 12th, 2018|

Mechanically-graded biomaterial for bone-tendon repair. (B) Bone-like and (C) tendon-like tissue patterning on mechanically-graded biomaterial in vivo. Tri, trichrome. With the combined use of macroscale biomechanical (material stiffness) and biochemical cues (growth factor biopatterning), Prof. Michelle Wang's [...]