Prof. JIANG Yangzi (姜洋子) received Bachelor (2007, Biology) and PhD (2012, Sports Medicine) in Zhejiang University, China, and received her postdoctoral training (2012-2018) at University of Pittsburgh, USA. Prof. Jiang joined CUHK in 2018 as Research Assistant Professor at institute for Tissue Engineering and Regenerative Medicine (iTERM), School of Biomedical Sciences (SBS), and Assistant Professor (by courtesy) at Department of Orthopaedics & Traumatology (ORT).

Currently, she focuses on various research areas on 1) Tissue engineering and regenerative medicine; 2) Tissue engineering and regenerative medicine; 3) Adult tissue specific stem/progenitor cells; 4) Regulating stem cells for cell-based therapy, etc.

You may see her recent publications for exploration and inspiration, and further scientific exchange and collaboration, if you are interested.  

  1. Cao, M., Ong, M., Yung, P., Tuan, R., & Jiang, Y. (2022). Role of synovial lymphatic function in osteoarthritis. Osteoarthritis and Cartilage, https://doi.org/10.1016/j.joca.2022.04.003
  2. Yang, J., Zhang, X., Chen, J., Heng, B., Jiang, Y., Hu, X., & Ge, Z. (2022). Macrophages promote cartilage regeneration in a time‐ and phenotype‐dependent manner. Journal of Cellular Physiology, 237(4), 2258-2270. https://doi.org/10.1002/jcp.30694
  3. Zhu, X., Lee, C., Xu, H., Wang, Y., Yung, P., Jiang, Y., & Lee, O. (2021). Phenotypic alteration of macrophages during osteoarthritis: A systematic review. Arthritis Research & Therapy, 23(1), 110. https://doi.org/10.1186/s13075-021-02457-3
  4. Jiang, Y. (2022). Osteoarthritis year in review 2021: Biology. Osteoarthritis and Cartilage, 30(2), 207-215. https://doi.org/10.1016/j.joca.2021.11.009
  5. Li, K., Jiang, Y., Yang, Z., Heng, B., Tian, H., & Ge, Z. (2021). Can Upregulation of Pluripotency Genes Enhance Stemness of Mesenchymal Stem Cells? Stem Cell Reviews, 17(4), 1505. https://doi.org/10.1007/s12015-021-10154-6
  6. Zhu, X., Chan, Y., Yung, P., Tuan, R., & Jiang, Y. (2021). Subchondral Bone Remodeling: A Therapeutic Target for Osteoarthritis. Frontiers in Cell and Developmental Biology, 8, 607764. https://doi.org/10.1007/s12015-021-10154-6
  7. Li, K., Ning, T., Wang, H., Jiang, Y., Zhang, J., & Ge, Z. (2020). Nanosecond pulsed electric fields enhance mesenchymal stem cells differentiation via DNMT1-regulated OCT4/NANOG gene expression. Stem Cell Research & Therapy, 11(1), 308. https://doi.org/10.3389/fcell.2020.607764
  8. Chen, J., Huang, Y., Yang, J., Li, K., Jiang, Y., Heng, B., . . . Ge, Z. (2020). Multiple nanosecond pulsed electric fields stimulation with conductive poly(l‐lactic acid)/carbon nanotubes films maintains the multipotency of mesenchymal stem cells during prolonged in vitro culture. Journal of Tissue Engineering and Regenerative Medicine, 14(8), 1136-1148. https://doi.org/10.1002/term.3088
  9. Zhou, Q., Cai, Y., Jiang, Y., & Lin, X. (2020). Exosomes in osteoarthritis and cartilage injury: Advanced development and potential therapeutic strategies. International Journal of Biological Sciences, 16(11), 1811-1820. https://doi/org/10.7150/ijbs.41637
  10. Jiang, Y., Wang, D., Blocki, A., & Tuan, R. (2020). Mesenchymal stem cells in musculoskeletal tissue engineering. In R., Lanza, R., Langer, J.P., Vacanti, A., Anthony. (Ed.). Principles of Tissue Engineering (5th, pp. 883-915). https://doi.org/10.1016/C2018-0-03818-9
  11. Jiang, Y., & Tuan, R. (2019). Role of NGF‐TrkA signaling in calcification of articular chondrocytes. The FASEB Journal, 33(9), 10231-10239. https://doi.org/10.1096/fj.201900970
  12. Li, L., Jiang, Y., Lin, H., Shen, H., Sohn, J., Alexander, P., & Tuan, R. (2019). Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production. Journal of Orthopaedic Translation, 18, 142-153. https://doi.org/10.1016/j.jot.2019.06.001
  13. Yang, L., Tang, C., Chen, Y., Ruan, D., Zhang, E., Yin, Z., Chen, X., Jiang, Y.,. . . Ouyang, H. (2019). Pharmacological Inhibition of Rac1 Activity Prevents Pathological Calcification and Enhances Tendon Regeneration. ACS Biomaterials Science & Engineering, 5(7), 3511-3522. https://doi.org/10.1021/acsbiomaterials.9b00335
  14. Sun, J., Ma, X., Chu, H., Feng, B., Tuan, R., & Jiang, Y. (2019). Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease Modeling. Frontiers in Bioengineering and Biotechnology, 7, 373. https://doi.org/10.3389/fbioe.2019.00373

To explore further on her scientific accomplishment, please visit https://www.iterm.cuhk.edu.hk/our-people/prof-jiang-yangzi/.