Updates on Publications by iTERM Faculty Members

Prof. Dan WANG (left), Prof. Elmer KER, Prof. Anna BLOCKI, Prof. Hon Fai CHAN, Prof. Yangzi JIANG (right)

Since the joining the Institute for Tissue Engineering and Regenerative Medicine (iTERM), Professors Anna BLOCKI, Hon Fai CHAN, Yangzi JIANG, Elmer KER, Dan WANG, were actively contributing to the strategic development of iTERM and the School of Biomedical Sciences (SBS) of The Chinese University of Hong Kong (CUHK). In the meantime, they were eagerly collaborating with scholars and researchers from various prestigious international institutions for publications and research endeavors.

      Prof. Anna BLOCKI

• Anne KRUGER-GENGE, Anna BLOCKI, Ralf-Peter FRANKE, Friedrich JUNG. “Vascular endothelial cell biology: an update.” International Journal of Molecular Sciences, 2019; 20(18):4411. 
• Marisa ASSUNCAOA, Christy Wingtung WONG, Joseph J. RICHARDSON, Rachel TSANG, Sebastian BEYER, Michael RAGHUNATHE, Anna BLOCKI. “Macromolecular dextran sulfate facilitates extracellular matrix deposition by electrostatic interaction independent from a macromolecular crowding effect.” Mater Sci Eng C Mater Biol Appl, 2020 Jan; 106:110280.
• Yangzi JIANG, Dan WANG, Anna BLOCKI, Rocky S. TUAN. “Mesenchymal stem cells in musculoskeletal tissue engineering.” Principles of Tissue Engineering, 2020, 883 – 915. 
• Dan WANG, Charmaine C M PUN, Shuting HUANG, Thomas C M TANG, Kevin K W HO, Benjamin B ROTHRAUFF, Patrick S H YUNG, Anna M BLOCKI, Elmer D F KER, Rocky S TUAN. “Tendon-derived Extracellular Matrix Induces Mesenchymal Stem Cell Tenogenesis via an Integrin/Transforming Growth Factor-β Crosstalk-Mediated Mechanism.” FASEB J, 2020.

      Prof. Hon Fai CHAN

• Yutong JING, Yalan ZHOU, Congxiang WANG, Jian LIU, Yonglong GUO, Shengru MAO, Hon Fai CHAN, Shibo TANG, Jiansu CHEN. “Establishment of a non-integrate iPS cell line CSUASOi002-A, from urine-derived cells of a female patient with macular corneal dystrophy carrying compound heterozygous CHST6 mutations.” Stem Cell Research, 2019; 41:101598. 
• Yalan ZHOU, Chengcheng DING, Shutao XIA, Yutong JING, Shengru MAO, Jian LIU, Juan CHEN, Hon Fai CHAN, Shibo TANG, Jiansu CHEN. “Establishment of induced pluripotent stem cell line CSUASOi003- A from an autosomal recessive retinitis pigmentosa patient carrying compound heterozygous mutations in CRB1 gene.” Stem Cell Research, 2020; 44:101742.
• Yalan ZHOU, Yutong JING, Shengru MAO, Jian LIU, Zekai CUI, Yini WANG, Juan CHEN, Hon Fai CHAN, Shibo TANG, Jiansu CHEN. “Establishment of Induced Pluripotent Stem Cell Line CSUASOi004-A by Reprogramming Peripheral Blood Mononuclear Cells of a PRPF6-related Dominant Retinitis Pigmentosa Patient.” Stem Cell Research, 2020; 45:101793. 
• Xiaoyu ZHAO, Yanlun ZHU, Andrew L. LASLETT, Hon Fai CHAN. “Hepatic Differentiation of Stem Cells in 2D and 3D Biomaterial Systems.” Bioengineering, 2020; 7(2): 47. 
• Zekai CUI, Yonglong GUO, Yalan ZHOU, Shengru MAO, Xin YAN, Yong ZENG, Chengcheng DING, Hon Fai CHAN, Shibo TANG, Luosheng TANG, Jiansu CHEN. “Transcriptomic Analysis of the Developmental Similarities and Differences Between the Native Retina and Retinal Organoids.” Investigative Ophthalmology & Visual Science, 2020; 61(3):6.

      Prof. Yangzi JIANG

• Long YANG, Chenqi TANG, Yangwu CHEN, Dengfeng RUAN, Erchen ZHANG, Zi YIN, Xiao CHEN, Yangzi JIANG, Youzhi CAI, Yang FEI, Shouan ZHU, Huanhuan LIU, Jiajie HU, Boon Chin HENG, Weishan CHEN, Weiliang SHEN, Hongwei OUYANG. “Pharmacological Inhibition of Rac1 Activity Prevents Pathological Calcification and Enhances Tendon Regeneration.” ACS Biomaterials Science & Engineering, 2019; 5 (7):3511-3522.
• La LI, Yangzi JIANG, Hang LIN, He SHEN, Jihee SOHN, Peter G ALEXANDER, Rocky S TUAN. “Muscle Injury Promotes Heterotopic Ossification by Stimulating Local Bone Morphogenetic protein-7 Production.” J Orthop Translat, 2019; 18:142-153.
• Yangzi JIANG, Rocky S. TUAN. “Role of NGF-TrkA signaling in calcification of articular chondrocytes.” FASEB Journal, 2019; 33(9):10231-10239.
• Jing SUN, Xun MA, Ho Ting CHU, Bo FENG, Rocky S TUAN, Yangzi JIANG. “Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease Modeling.” Front Bioeng Biotechnol, 2019; 7:373.
• Quanfa ZHOU, Youzhi CAI, Yangzi JIANG, Xiangjin LIN. “Exosomes in Osteoarthritis and Cartilage Injury: Advanced Development and Potential Therapeutic Strategies.” International Journal of Biological Sciences, 2020; 16(11):1811-1820.
• Yangzi JIANG, Dan WANG, Anna BLOCKI, Rocky S. TUAN. “Mesenchymal stem cells in musculoskeletal tissue engineering.” Principles of Tissue Engineering, 2020, 883 – 915. 

     Prof. Elmer KER

• Shanjani, Y., Siebert, S.M., Ker, D.F.E., Mercado-Pagan, A.E., and Yang, Y.P. (2020) “Acoustic Patterning of Growth Factor for 3D Tissue Engineering” Tissue Engineering Part A (in press).
• Wang, D., Gilbert, J.R., Zhang, X., Zhao, B., Ker, D.F.E., Cooper, G.M (2020) “Calvarial versus long bone implications for tailoring skeletal tissue engineering” Tissue Engineering Part B 26, 1, pg. 46 – 63.
• Ker, D.F.E., Yang, Y.P. (2019) “Ruminants: Evolutionary past and future impact” Science (Perspective) 364, 6446, pg. 1130.
• Nishimura K., Ker, D.F.E., and Bise, R. (2019) “Cell Region Recognition in Microscopic Images Using Weakly Supervised Learning” (MIRU’19) 22nd Symposium on Image Recognition and Understanding (presented 29th Jul 2019 – 1st Aug 2019, Osaka, Japan). MIRU2019_paper_25
• Nishimura K., Ker, D.F.E., and Bise, R. (2019) “Weakly Supervised Cell Segmentation in Dense By Propagating from Detection Map” (MICCAI’19) Medical Image Computing and Computer Assisted Intervention (presented 13th Oct 2019 – 17th Oct 2019, Shenzhen, China). Weakly Supervised Cell Segmentation in Dense By Propagating from Detection Map
• Ker, D.F.E., Wang, D., Sharma, R., Zhang, B., Passarelli, B., Neff, N., Li, C., Maloney, W., Quake, S., Yang, Y.P. (2018) “Identifying deer antler uhrf1 proliferation and s100a10 mineralization genes using comparative RNA-seq” Stem Cell Research & Therapy 9, 1, pg. 292.
• Ker, D.F.E.*^, Wang, D.*, Behn, A.W., Wang, E.T.H., Zhang, X., Zhou, B.Y., Mercado-Pagan, A.E., Kim, S., Kleimeyer, J., Gharaibeh, B., Shanjani, Y., Nelson, D., Safran, M., Cheung E., Campbell, P., Yang, Y.P.^ (2018) “Functionally-Graded, Bone- and Tendon-Like Polyurethane for Rotator Cuff Repair” Advanced Functional Materials 28,20, pg. 201707107 *Co-first authors, ^Co-corresponding authors.

Picture 1: Mechanically-robust, 3D-Printed biomaterials for tendon repair

Picture 2: Computer-vision based algorithms detect cells without need for staining reagents, enabling continuous cell monitoring for biological research and stem cell manufacturing.

      Prof. Dan WANG

• Dai Fei Elmer KER, Dan WANG, Anthony William BEHN, Evelyna Tsi Hsin WANG, Xu ZHANG, Benjamin Yamin ZHOU, Ángel Enrique MERCADO-PAGAN, Sungwoo KIM, John KLEIMEYER, Burhan GHARAIBEH, Yaser SHANJANI, Drew NELSON, Marc SAFRAN, Emilie CHEUNG, Phil CAMPBELL, Yunzhi Peter YANG. “Functionally Graded, Bone‐ and Tendon‐Like Polyurethane for Rotator Cuff Repair.” Advanced Functional Materials, 2018; 28(20):1707107.(co-1st author)
• Ker, D.F.E., Wang, D., Sharma, R., Zhang, B., Passarelli, B., Neff, N., Li, C., Maloney, W., Quake, S., Yang, Y.P. (2018) “Identifying deer antler uhrf1 proliferation and s100a10 mineralization genes using comparative RNA-seq” Stem Cell Research & Therapy 9, 1, pg. 292.
• Yangzi JIANG, Dan WANG, Anna BLOCKI, Rocky S. TUAN. “Mesenchymal stem cells in musculoskeletal tissue engineering.” Principles of Tissue Engineering, 2020, 883 – 915. 
• Dan WANG, James R GILBERT, Xu ZHANG, Bingkun ZHAO, Dai Fei Elmer KER, Gregory M COOPER. “Calvarial Versus Long Bone: Implications for Tailoring Skeletal Tissue Engineering.” Tissue Eng Part B Rev, 2020; 26(1):46-63.
• Dan WANG, Charmaine C M PUN, Shuting HUANG, Thomas C M TANG, Kevin K W HO, Benjamin B ROTHRAUFF, Patrick S H YUNG, Anna M BLOCKI, Elmer D F KER, Rocky S TUAN. “Tendon-derived Extracellular Matrix Induces Mesenchymal Stem Cell Tenogenesis via an Integrin/Transforming Growth Factor-β Crosstalk-Mediated Mechanism.” FASEB J, 2020.